Direct NF-kB suppression, anti-inflammatory, gut-skin axis
What is KLOW?
KLOW is the anti-inflammatory upgrade to the GLOW blend. It adds KPV — a tripeptide derived from alpha-MSH — to the three-compound GLOW foundation (BPC-157, TB-500, GHK-Cu), creating a four-peptide 80mg vial.
The distinguishing mechanism of KLOW is KPV's direct suppression of NF-kB, the master regulator of inflammatory signaling. While BPC-157 and GHK-Cu have indirect anti-inflammatory effects, KPV gates inflammation at the cellular signaling level — making KLOW particularly relevant for conditions driven by chronic or systemic inflammation rather than acute injury alone.
Research on KPV suggests particular relevance for gut-skin axis conditions: inflammatory bowel disease, eczema, psoriasis, and chronic inflammatory skin issues that have a gut-driven inflammatory component. KLOW packages this alongside the musculoskeletal repair and collagen support of GLOW.
Reconstitution Guide
Standard protocol: add 2mL bacteriostatic water to the 80mg vial.
Concentration
40 mg/mL
Units per dose
10 units
Volume per dose
0.1 mL
Doses per vial
~20
At 10 units (0.1mL): BPC-157 ~500mcg · TB-500 ~500mcg · GHK-Cu ~2.5mg · KPV ~500mcg. Use the Reconstitution Calculator for custom dilutions.
FAQ
What is KLOW?+
KLOW is a 4-peptide blend containing BPC-157 (10mg), TB-500 (10mg), GHK-Cu (50mg), and KPV (10mg) in a single 80mg vial. It is the anti-inflammatory upgrade to the GLOW blend, adding KPV's direct NF-kB suppression to the repair and collagen stack.
What does KPV add to the KLOW blend?+
KPV (Lys-Pro-Val) is a tripeptide derived from alpha-MSH that directly suppresses NF-kB — the master regulator of inflammatory signaling. This makes KLOW more suitable than GLOW for users dealing with systemic inflammation, gut issues, autoimmune-related tissue damage, or chronic inflammatory skin conditions.
How do you reconstitute KLOW?+
Add 2mL of bacteriostatic water to the 80mg KLOW vial. This yields 40mg/mL total blend concentration. At 10 units on a U-100 insulin syringe (0.1mL), you deliver 4mg of total blend: approximately 500mcg BPC-157, 500mcg TB-500, 2.5mg GHK-Cu, and 500mcg KPV.
Who should use KLOW instead of GLOW?+
Choose KLOW when dealing with systemic inflammation, gut issues, autoimmune conditions, or chronic inflammatory skin conditions like eczema and psoriasis. Choose GLOW for pure musculoskeletal repair or anti-aging without significant inflammatory component.