How Much BAC Water for Tirzepatide?
The answer depends on your vial size and target concentration. Here are the standard reconstitution volumes, dose tables, and draw unit calculations for every common tirzepatide vial size.
The Short Answer
For a 5mg vial (most common):
- • 1mL BAC water → 5mg/mL concentration
- • 2mL BAC water → 2.5mg/mL concentration
General rule:
- • 1mL per 5mg = 5mg/mL (standard)
- • 2mL per 5mg = 2.5mg/mL (more precise draws)
Tirzepatide Reconstitution Table
Resulting concentration in mcg/mL based on vial size and BAC water volume added.
| Vial size | 1mL BAC water | 2mL BAC water | Notes |
|---|---|---|---|
| 2.5mg | 2,500 mcg/mL | 1,250 mcg/mL | Starter dose vial |
| 5mg | 5,000 mcg/mL | 2,500 mcg/mL | Standard vial |
| 7.5mg | 7,500 mcg/mL | 3,750 mcg/mL | |
| 10mg | 10,000 mcg/mL | 5,000 mcg/mL | |
| 12.5mg | 12,500 mcg/mL | 6,250 mcg/mL | |
| 15mg | 15,000 mcg/mL | 7,500 mcg/mL | Max approved dose |
Protocol reconstitution calculator
Enter your vial size and dose — get exact draw units
Draw Units by Dose
Using a standard 1mL insulin syringe (100 units = 1mL). Assumes standard tirzepatide titration schedule doses.
| Dose target | At 5mg/mL (1mL BAC) | At 2.5mg/mL (2mL BAC) |
|---|---|---|
| 0.5mg (500mcg) | 10 units (0.1mL) | 20 units (0.2mL) |
| 1mg (1,000mcg) | 20 units (0.2mL) | 40 units (0.4mL) |
| 2.5mg (2,500mcg) | 50 units (0.5mL) | 100 units (1.0mL) |
| 5mg (5,000mcg) | 100 units (1.0mL) | 200 units (2.0mL) |
| 7.5mg (7,500mcg) | 150 units (1.5mL) | 300 units (3.0mL) |
| 10mg (10,000mcg) | 200 units (2.0mL) | 400 units (4.0mL) |
Calculate your exact draw units
Enter your vial size, BAC water volume, and target dose. The reconstitution calculator outputs the exact units to draw on any syringe size.
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How to Reconstitute Tirzepatide
Let the vial reach room temperature
Remove from refrigeration 15–30 minutes before mixing. Cold peptide and room-temperature BAC water can affect stability.
Draw the correct volume of BAC water
Using a fresh needle and syringe, draw 1mL (or 2mL, based on your target concentration) of bacteriostatic water.
Inject BAC water slowly into the vial
Angle the needle so the water runs down the side of the vial — do not inject directly onto the lyophilized powder. Add slowly to avoid foaming.
Do not shake — gently swirl
Shaking can degrade peptides. Roll the vial gently between your palms or swirl until the powder is fully dissolved. The solution should be clear and colorless.
Log the reconstitution date immediately
The 28-day clock starts now. Log the date, BAC water volume, vial size, and resulting concentration before refrigerating. Protocol handles this in the vial management screen.
Refrigerate at 2–8°C (36–46°F)
Do not freeze. Use within 28 days. Protect from light.