Research/Compounds/TRT & Hormone Optimization

TRT & Hormone Optimization

Research profiles for testosterone replacement therapy compounds, aromatase inhibitors, SERMs, and hormone precursors. Evidence-graded dosing, mechanism, and monitoring guides.

Testosterone Cypionate
Most common TRT ester — weekly or bi-weekly injection
FDA Approved
Testosterone Enanthate
Long-acting ester — 5-7 day half-life
FDA Approved
Testosterone Propionate
Short-acting ester — every other day protocol
FDA Approved
Anastrozole
Aromatase inhibitor — estrogen management on TRT
FDA Approved
Enclomiphene
SERM — preserves fertility while raising testosterone
Research
Clomiphene (Clomid)
SERM — HPG axis stimulation, fertility preservation
FDA Approved
DHEA
Hormone precursor — adrenal androgen
OTC
Pregnenolone
Master hormone precursor — neurosteroid
OTC
Progesterone
Hormone balancing — used in both men and women
FDA Approved
Estradiol
Primary estrogen — critical for bone, cardiovascular, cognitive health
FDA Approved
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